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Mesothelioma treatmentMesothelioma is almost always fatal, but steps can be taken to prolong life. So far, treatment options include:

Surgery - Depending on how far the cancer has progressed, it may be necessary to remove part of the lining of the chest or abdomen and some of the tissue around either. In more advanced cases, a doctor may have to remove one of the patient's lungs, part of the diaphragm, or the pericardium.

Draining fluid from the lungs, abdomen or pericardium is another surgical procedure. This treatment is used to ease a patient's pain or discomfort, and sometimes to prevent fluid from building up again, but it is not a cure for the disease.

Chemotherapy - This is the use of drugs for treating cancer. The drugs can be ingested in pill form or they can be injected by needle into a vein or muscle. Chemotherapy therapy is systemic therapy, which means that the drug enters the bloodstream and circulates throughout the body (through the whole system) to reach and destroy the cancer cells.

Several anti-cancer drugs have been used to treat mesothelioma. The drug most effective when given alone is doxorubicin or Adriamycin. Cisplatin, gemcitabine, methotrexate, vinorelbine, and capecitabine are other drugs that can be given as well.

Often anti-cancer drugs are combined in their dosage to try to increase their effectiveness (drug cocktail). Combinations of drugs used in the treatment of mesothelioma include:

  • cisplatin, mitomycin, and vinblastine
  • cisplatin and doxorubicin
  • cisplatin, cyclophosphamide and doxorubicin
  • cisplatin and gemcitabine
  • methotrexate and vincristine

Other drugs such as paclitaxel and irinotecan are currently being studied to determine their effectiveness in treating mesothelioma.

Chemotherapy drugs kill cancer cells but also damage some normal cells. Therefore, your doctor will pay careful attention to avoiding or minimizing side effects, which depend on the specific drugs, the amount taken, and the length of treatment. Temporary side effects might include nausea and vomiting, loss of appetite, loss of hair, and mouth sores.

Radiation Therapy -

Radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors. The radiation may come from a machine outside the body (external radiation), or from putting materials that produce radiation through thin plastic tubes in the area where the cancer cells are found (internal radiation). Factors which can limit the application of this treatment include the volume of the tumor and how near it is to vital organs. The side effects can be severe.

In addition to traditional treatments, new mesothelioma cancer treatments are continually being tested through medical research studies. These treatments are called clinical trials, and they help researchers determine whether new treatments are safe and effective for general use, while giving patients with few treatment options an opportunity to try new treatments.

More scientific updates can be found at:

Long-term collaboration yields cancer-fighting compound

Ten Best Readings On Lung Cancer and Mesothelioma

Open-Label Study of ALIMTA (pemetrexed) Alone or In Combination With Cisplatin for Patients With Malignant Mesothelioma

How a common protein becomes a cancer killer

Earliest known facts about asbestos

Improving Our Management of Non-Small-Cell Lung Cancer and Mesothelioma

Having mesothelioma is one thing, dealing with it is quite another. It's time now to get plugged into the support network of mesothelioma survivors and cancer mailing lists that are online. Turn now to:

Next > Chapter 7 - Mesothelioma Coping

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Copyright 2004 Barbara Ling
http://www.barbaraling.com

The content of this mesothelioma web site has not been prepared or endorsed by any physicians or other licensed medical professionals. Nothing on this site should be taken as medical advice. The designer of the Mesothelioma Resources Free eBook is not a physician nor trained medical professional and nothing they say should be taken as medical or legal advice. The purpose of this site is to provide patients and their families with useful information and access to other mesothelioma resources, which may be helpful. Patients are encouraged to consult with their physician for medical advice and with an mesothelioma attorney for legal advice.

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